NSAIDS Might Interfere with Antidepressants

 

Certain types of antidepressants may not work as well in people who take non-steroidal anti-inflammatory drugs (NSAIDs), suggests a new study published online in the Proceedings of the National Academy of Sciences. The researchers couldn't separate people who took an NSAID only once or twice during the 12 week study duration from those who used them regularly. The authors also didn't find that NSAIDs interfered with other, non-SSRI antidepressants. The authors said that based on the data they used, it was impossible to prove that NSAIDs stop SSRIs from working. It's possible, for example, that people who have underlying conditions that require drugs such as aspirin and ibuprofen have more trouble recovering from depression.

Dr. Solomon Snyder, a neuroscientist at Johns Hopkins Medical School in Baltimore who will have a commentary coming out when the study appears in print, said in an email that the findings show that "if someone is receiving SSRIs, he/she should avoid NSAIDs." However, he told Reuters Health, "Such a recommendation may well be controversial and cause difficulties for patients with arthritis and other conditions which benefit from NSAIDs."

Full article from Reuters Health on Medscape…

 

5/11